MELATONIN

 MELATONIN

1. Description

Chemical name:

N-Acetyl-5-Methoxytryptamine ; N-(2-(5-methoxyindol-3-yl)ethyl)acetamide; Melatonin; L-Arabinitol; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide;

3-N-Acetyl-5-methoxyl tryptamine; Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;

N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide

Molecular formula: C₁₃H₁₆N₂O₂ 

Molecular weight: 232,28 

 CAS No：73-31-4 

Structural formula: 

   
 

2. Specification  

3. Introduction

Melatonin is mainly an amine hormone produced by the pineal gland of mammals and humans.

Lerner (1959) isolated a hormone in the pineal gland for the first time. Because this hormone can brighten a cell that produces melanin, the prefix Mela is chosen; at the same time, it is derived from serotonin (serotonin). ) Is derived from it, so the suffix tonin is used. Therefore, this pineal hormone is named Melatonin (melatonin). The content of melatonin in the body is very small, present at the level of pg (1×10-12 g). In recent years, extensive research has been conducted on the biological functions of melatonin at home and abroad, especially as a dietary supplement. It has shown that it has many physiological functions such as promoting sleep, regulating jet lag, anti-aging, regulating immunity, and anti-tumor and so on.

4. Mainly usages

Melatonin can improve sleep, shorten the time to wake up and fall asleep before going to bed, and improve sleep quality. The number of awakenings during sleep is significantly reduced, the light sleep phase is short, the deep sleep phase is prolonged, and the wake-up threshold the next morning decreases. There is a strong function of adjusting the time difference. It can be used in whitening and moisturizing cosmetics, and is also commonly used in hair growth products. Extensive research on the biological functions of melatonin at home and abroad, especially as a dietary supplement, has shown that it has many physiological functions such as promoting sleep, regulating jet lag, anti-aging, regulating immunity, and anti-tumor. The health care function of melatonin at home and abroad involves regulating endocrine (inhibiting ovulation), protecting against encephalitis virus infection, reducing its mortality after infection, AIDS treatment and cardiovascular protection, etc.